منابع مشابه
Histological and clinical evolution of lupus nephritis.
In recent years, lupus nephritis has become the major complication and the most pressing problem in patients suffering from lupus erythematosus disseminatus. The clinical course of the disease was different 15 years ago, when Keith (1940) wrote that "renal insufficiency does not play an important role in causing death". At that time patients usually died of a "lupus crisis" or as a result of co...
متن کاملBiomarkers for Lupus Nephritis: A Critical Appraisal
Kidney disease is one of the most serious manifestations of systemic lupus erythematosus (SLE). Despite the improvement in the medical care of SLE in the past two decades, the prognosis of lupus nephritis remains unsatisfactory. Besides exploring more effective but less toxic treatment modalities that will further improve the remission rate, early detection and treatment of renal activity may s...
متن کاملThe prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
متن کاملPlasma CD147 reflects histological features in patients with lupus nephritis.
OBJECTIVE A glycosylated transmembrane protein, CD147, has been implicated in regulating lymphocyte responsiveness and leukocyte recruitment. As lupus nephritis (LN) often follows a relapsing-remitting disease course, accurate understanding of the disease activity would be extremely helpful in improving prognosis. Unfortunately, neither clinical nor serological data can accurately reflect the h...
متن کاملAssociation of Urinary Lipocalin-2 with Lupus Nephritis
Objective(s): Lupus nephritis (LN) is the main cause of mortality and disability in systemic lupus erythematosus (SLE) patients. Therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. The aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in SLE patients. Materi...
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ژورنال
عنوان ژورنال: Hong Kong Journal of Nephrology
سال: 2000
ISSN: 1561-5413
DOI: 10.1016/s1561-5413(09)60027-2